澳洲胎牛血清（特级）辐照 

科研：干细胞、昆虫细胞、原代体细胞、传代体细胞、基因改造细胞、肿瘤细胞、异倍体细胞等细胞的体外培养与保存。

1)干细胞：间充质干细胞、神经干细胞、胚胎干细胞、造血干细胞。

2)昆虫细胞：SF9(草地贪夜蛾细胞)。

3)原代体细胞：

原代肿瘤细胞、原代成纤维细胞、原代内皮细胞、原代肌肉细胞、原代神经细胞、原代免疫细胞。

4)传代体细胞：

成纤维细胞：3T3(小鼠胚胎成纤维细胞)、L929(小鼠成纤维细胞)、MRC-5(人胚肺成纤维细胞)等。

内皮细胞：ECV304(人脐静脉内皮细胞株)、HUVECs(人脐静脉内皮细胞)等。

上皮细胞：RLE-6TN(大鼠肺上皮细胞)、CHO-K1(仓鼠卵巢上皮细胞)等。

肌肉细胞：HA-VSMC(人主动脉血管平滑肌细胞)等。

免疫细胞：OCI-LY1(人B淋巴细胞)、HMy2.CIR(人B淋巴母细胞)、Ana-1(小鼠巨噬细胞)、NR8383(大鼠肺泡巨噬细胞)等。

5)基因改造细胞：

HEK293(转染腺病毒E1A基因的人胚肾细胞)、293T(表达SV40大T抗原人胚肾细胞)、杂交瘤细胞、永生化的原代体细胞等。

6)肿瘤细胞：

Hela(人子宫颈癌细胞)、HepG2(人肝癌细胞株)、A549(人非小细胞肺癌细胞系)、MCF-7(乳腺癌细胞中的常用亚型)、sp2/0(骨髓瘤细胞)、YAC-1(小鼠淋巴瘤细胞)、A3(人T淋巴细胞白血病细胞)、RAW 264.7(小鼠单核巨噬细胞白血病细胞)、SH-SY5Y(人神经母细胞瘤细胞)、U251(人脑神经胶质瘤细胞)等。

7)异倍体细胞：

CHO(中国仓鼠卵巢细胞)、Vero(非洲绿猴肾细胞)、BHK-21(乳仓鼠肾细胞)等。

工业：类器官培养、干细胞扩增、干细胞诱导分化、干细胞改造及保存、免疫细胞扩增、免疫细胞诱导分化、免疫细胞改造及保存、病毒包装、蛋白表达、质粒转化、细胞药效评价等。

成功案例：

HEK293(转染腺病毒E1A基因的人胚肾细胞)、293T(表达SV40大T抗原人胚肾细胞)、293E(E转化人胚肾293细胞)、Vero(非洲绿猴肾 细胞)、CHO(中国仓鼠卵巢细胞)、LLC(小 鼠肺癌细胞)、Hela(人子宫颈癌细胞)、CT-26(小鼠结肠癌细胞)、C4-2(人前列腺癌细胞)、MDA-MB-231(人乳腺癌细胞株)、H1299(人肺癌细胞)、H460(人肺癌细胞)、SF9(草地贪夜蛾细胞)、BMDM(骨髓衍生的巨嘡细胞)、RAW246.7(小鼠单核巨噬细胞)、THP-1(人急性单核白血病细胞)、C2C12(小鼠成肌细胞)、HS729(人横纹肌肉瘤细胞)、肾上皮细胞、原代成纤维细胞、原代B淋巴细胞、原代上皮细胞、两栖类动物细胞、原代小鼠心肌细胞、小鼠神经元细胞、原代人神经干细胞、神经胶质细胞、原代神经细胞、肾间充质干细胞、原代小鼠骨髓间充质干细胞等等。

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49. （2024）A zinc metabolism-related gene signature for predicting prognosis and characteristics of breast cancer； Frontiers in Immunology
50. （2024）A cavity induced mode hybridization plasmonic sensor for portable detection of exosomes； Biosensors and Bioelectronics
51. （2023）A presumed missense variant in the U2AF2 gene causes exon skipping in neurodevelopmental diseases； journal of human genetics
52. （2023）Aberrant DNA Methylation Patterns of Deleted in Liver Cancer 1 Isoforms in Hepatocellular Carcinoma； DNA and Cell Biology
53. （2023）Biocompatible PVTF Coatings on Ti with Improved Bonding Strength； Coatings
54. （2023）Aflatoxin B1 can aggravate BALB/c mice allergy to ovalbumin through changing their Th2 cells immune responses； Toxicon
55. （2023）Anti-tumor effect of infant-derived Enterococcus via the inhibition of proliferation and inflammation as well as the promotion of apoptosis； Food & Function
56. （2023）Antitumor Effects of Poplar Propolis on DLBCL SU-DHL-2 Cells； Foods
57. （2023）Carbon dots based on targeting unit inheritance strategy for Golgi apparatus-targeting imaging； Frontiers of Materials Science
58. （2023）Cardioprotective and anti-inflammatory effects of Caveolin 1 in experimental diabetic cardiomyopathy； Clinical Science
59. （2023）CCDC115 inhibits autophagy-mediated degradation of YAP to promote cell proliferation； FEBS Letters
60. （2023）CDK4/6 inhibitor modulating active and quiescent intestinal stem cells for prevention of chemotherapy-induced diarrhea； Journal of Pathology
61. （2023）circPHF16 suppresses prostate cancer metastasis via modulating miR-581/RNF128/Wnt/β-catenin pathway； Cellular Signalling
62. （2023）Clinical and Functional Characterization of Novel AGL Variants in Two Families with Glycogen Storage Disease Type III； International Journal of Endocrinology
63. （2023）Coelonin protects against PM2.5-induced macrophage damage via suppressing TLR4/NF-κB/COX-2 signaling pathway and NLRP3 inflammasome activation in vitro； Environmental Toxicology
64. （2023）Blue light pollution causes retinal damage and degeneration by inducing ferroptosis； Journal of Photochemistry and Photobiology B： Biology
65. （2023）Deubiquitinase USP47 attenuates virus-induced type I interferon signaling； International Immunopharmacology
66. （2023）Development of a Two-Step Hydrolysis Hypoallergenic Cow’s Milk Formula and Evaluation of Residue Allergenicity by Peptidomics and Immunoreactivity Analysis； Journal of agricultural and food chemistry
67. （2023）Fusion protein and hemagglutinin of canine distemper virus co-induce apoptosis in canine mammary tumor cells； Journal of Cancer Research and Clinical Oncology
68. （2023）Gallic acid in theabrownin suppresses cell proliferation and migration in non?small cell lung carcinoma via autophagy inhibition； Oncology Letters
69. （2023）Elevated exosome-transferrable lncRNA EPB41L4A-AS1 in CD56bright NK cells is responsible for the impaired NK function in neuroblastoma patients by suppressing cell glycolysis； Clinical Immunology
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93. （2023）Oral exposure to Staphylococcus aureus enterotoxin B could promote the Ovalbumin-induced food allergy by enhancing the activation of DCs and T cells； Carcinogenesis
94. （2023）p38 mediates T-2 toxin-induced Leydig cell testosterone synthesis disorder4； Ecotoxicology and Environmental Safety
95. （2023）Nanofat lysate ameliorates pain and cartilage degradation of osteoarthritis through activation of TGF-β-Smad2/3 signaling of chondrocytes； Front. Pharmacol
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102. （2023）Piceatannol protects against age-related hearing loss by inhibiting cellular pyroptosis and inflammation through regulated Caspase11-GSDMD pathway； Biomedicine & Pharmacotherapy
103. （2023）Polarized P(VDF-TrFE) film promotes skin wound healing through controllable surface potential； Colloids and Surfaces B： Biointerfaces
104. （2023）Preliminary Study on Human Adipose Stem Cells Promoting Skin Wound Healing through Notch Signaling Pathway； Current Stem Cell Research & Therapy
105. （2023）Preparation and characterization of astaxanthin-loaded microcapsules and its application in effervescent tablets； J Sci Food Agric
106. （2023）Syntheses， structures， and the in vitro anticancer mechanism of triorganotin (IV) complexes based on 4，4′-stilbenedicarboxylic acid； Applied Organometallic Chemistry
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108. （2023）The anti-inflammatory effect of lutein in broilers is mediated by regulating Toll-like receptor 4/myeloid-differentiation-factor 88 signaling pathway； Poultry Science
109. （2023）TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling； Journal of Experimental & Clinical Cancer Research
110. （2023）Transcriptional activation of Mink enteritis virus VP2 by the C-terminal of its NS1 protein； Virus Genes
111. （2023）T-2 toxin inhibits osteoblastic differentiation and mineralization involving mutual regulation between Wnt signaling pathway and autophagy； Chemico-Biological Interactions
112. （2023）The panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro； BMC Microbiology
113. （2023）USP15 Represses Hepatocellular Carcinoma Progression by Regulation of Pathways of Cell Proliferation and Cell Migration： A System Biology Analysis； Cancers
114. （2023）VIM?AS1 promotes proliferation and drives enzalutamide resistance in prostate cancer via IGF2BP2?mediated HMGCS1 mRNA stabilization； International Journal of Oncology
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116. （2022）α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization； eLife
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118. （2022）Tumor suppressive role of microRNA-139-5p in bone marrow mesenchymal stem cells-derived extracellular vesicles in bladder cancer through regulation of the KIF3A/p21 axis； Cell Death & Disease
119. （2022）The osteogenic response to chirality-patterned surface potential distribution of CFO/P (VDF-TrFE) membranes； Biomaterials Science
120. （2022）Targeting MDC1 promotes apoptosis and sensitizes Imatinib resistance in CML cells by mainly disrupting non-homologous end-joining repair； Medical Oncology
121. （2022）Targeting PI3K/AKT/mTOR pathway to enhance the anti-leukemia efficacy of venetoclax； Experimental Cell Research
122. （2022）Tanshinol suppresses osteosarcoma by specifically inducing apoptosis of U2-OS cells through p53-mediated mechanism； Journal of Ethnopharmacology
123. （2022）Salivary non‐apoptotic tumoral microvesicles： A potential progressive marker in oral cancer patients； Journal of Cellular and Molecular Medicine
124. （2022）Orange-emissive carbon quantum dots for ligand-directed Golgi apparatus-targeting and in vivo imaging； Biomaterials Science
125. （2022）Nanofat lysate ameliorates pain and cartilage degradation of osteoarthritis through activation of TGF-β–Smad2/3 signaling of chondrocytes； Frontiers in Pharmacology
126. （2022）METTL14-mediated Lnc-LSG1 m6A modification inhibits clear cell renal cell carcinoma metastasis via regulating ESRP2 ubiquitination； Molecular Therapy-Nucleic Acids
127. （2022）Intra-Articular Injection of Adipose-Derived Stem Cells Ameliorates Pain and Cartilage Anabolism/Catabolism in Osteoarthritis： Preclinical and Clinical Evidences； Frontiers in Pharmacology
128. （2022）In Vitro Effect of Flavonoids on Basophils Degranulation andIntestinal Epithelial Barrier Damage Induced by ω-5Gliadin-Derived Peptide； Foods
129. （2022）Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit theJAK-STAT Signaling Pathway in HD11 Cells； Viruses
130. （2022）Global miRNA dosage control of embryonic germ layer Specification； Nature
131. （2022）Highly Accessible Computational Prediction and In Vivo/In Vitro Experimental Validation： Novel Synthetic Phenyl Ketone Derivatives as Promising Agents against NAFLD via Modulating Oxidoreductase Activity； Oxidative Medicine and Cellular Longevity
132. （2022）EI24 promotes cell adaption to ER stress by coordinating IRE1 signaling and calcium homeostasis； EMBO Reports
133. （2022）Electroactive extracellular Matrix/Polypyrrole composite films and their microenvironmental effects on osteogenic differentiation of BMSCs； Chemical Engineering Journal
134. （2022）Cyclooxygenase-2-targeting fluorescent carbon dots for the selective imaging of Golgi apparatus； Dyes and Pigments
135. （2022）A High Hepatic Uptake of Conjugated Bile Acids PromotesColorectal Cancer—Associated Liver Metastasis； cells
136. （2021）An Investigation into the Interaction between Double Hydroxide-Based Antioxidant Benzophenone Derivatives and Cyclooxygenase 2； molecules
137. （2021）Association of human breast cancerCD44-/CD24-cells with delayed distantmetastasis； Elife
138. （2021）Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation； Nature Immunology
139. （2021）Caveolin 1 Reduces High Glucose-Induced Hypertrophy and Infl ammatory Fibrosis of H9C2 Cardiomyocytes By Inhibiting NF-κB Signaling；
140. （2021）Dihydrotanshinone I inhibits aortic valve interstitial cell calcification via the SMAD1/5/8/NF-κB/ERK pathway； Biomedicine & Pharmacotherapy
141. （2021）Exosomes released from CaSR‐stimulated PMNs reduce ischaemia/reperfusion injury； Oxidative medicine and cellular longevity
142. （2021）Farrerol Directly Targets GSK-3β to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries； Oxidative Medicine andCellular Longevity
143. （2021）Hyaluronic acid dissolving microneedle patch loaded with rice fermentation filtrate for improved moisturizing and anti-wrinkle effects.； Detergent & Cosmetics
144. （2021）Epithelial cell adhesion molecule promotes breast cancer resistance protein‐mediated multidrug resistance in breast cancer by inducing partial epithelial–mesenchymal transition； Cell Biology International
145. （2021）Inhibition of Nrf2-mediated glucose metabolism by brusatol synergistically sensitizes acute myeloid leukemia to Ara-C； Biomedicine & Pharmacotherapy
146. （2021）Light-induced osteogenic differentiation of BMSCs with graphene/TiO2 composite coating on Ti implant； Colloids and Surfaces B： Biointerfaces
147. （2021）Nicotine aggravates vascular adiponectin resistance via ubiquitin-mediated adiponectin receptor degradation in diabetic Apolipoprotein E knockout mouse； Cell death & disease
148. （2021）Osteocyte exosomes accelerate benign prostatic hyperplasia development； Molecular and Cellular Endocrinology
149. （2021）Pain relief and cartilage repair by Nanofat against osteoarthritis： preclinical and clinical evidence； Stem Cell Res Ther
150. （2021）Screening of anti-allergy Lactobacillus and its effect on allergic reactions in BALB/c mice sensitized by soybean protein； Journal of Functional Foods
151. （2021）QTMP， a novel thiourea polymer， causes DNA damage to exert anticancer activity and overcome multidrug resistance in colorectal cancer cells； Frontiers in Oncology
152. （2021）ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer； Cancer Letters
153. （2021）VHH212 nanobody targeting the hypoxia-inducible factor 1α suppresses angiogenesis and potentiates gemcitabine therapy in pancreatic cancer in vivo； Cancer biology & medicine
154. （2021）Ubiquitin D Promotes Progression of Oral Squamous Cell Carcinoma via NF-Kappa B Signaling； Molecules and Cells
155. （2020）Ultra-low level detection of hepatocellular carcinoma global methylation using a AuNP modified carbon fiber microelectrode； RSC advances
156. （2020）Synthesis of Acid-Labile Poly(Doxazolidine) as a Polyprodrug with an Ultra-High Drug Content for Self-Delivery of High-Performance Chemotherapeutics； Molecular Pharmaceutics
157. （2020）Rapid synthesis of BN co-doped yellow emissive carbon quantum dots for cellular imaging； Optical Materials
158. （2020）Polarization behavior of bone marrow-derived macrophages on charged P(VDF-TrFE) coatings； Biomaterials science
159. （2020）Phospholipid-Coated Guanosine Diphosphate Auxiliary CaP Active Nanoparticles Can Systematically Improve the Efficiency of Gene Therapy for Cancer Disease； ACS Biomaterials Science & Engineering
160. （2020）pH-responsive surface charge reversal carboxymethyl chitosan-based drug delivery system for pH and reduction dual-responsive triggered DOX release； Carbohydrate Polymers
161. （2020）Novel Platform for Surface-Mediated Gene Delivery Assisted with Visible-Light Illumination； ACS Applied Materials & Interfaces
162. （2020）Inhibition of mTORC1/P70S6K pathway by Metformin synergistically sensitizes Acute Myeloid Leukemia to Ara-C； Life Sciences
163. （2020）Histone H4R3 symmetric di-methylation by Prmt5 protects against cardiac hypertrophy via regulation of Filip1L/β-catenin； Pharmacological Research
164. （2020）Enhancing Osteogenic Differentiation of BMSCs on High Magnetoelectric Response Films； Materials Science and Engineering
165. （2019）Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-?B pathway in chondrocytes； Aging-US
166. （2019）Comprehensive Evaluation of Surface Potential Characteristics on Mesenchymal Stem Cells’ Osteogenic Differentiation； ACS applied materials & interfaces
167. （2019）Overexpression of zinc finger protein 384 (ZNF 384)， a poor prognostic predictor， promotes cell growth by upregulating the expression of Cyclin D1 in Hepatocellular carcinoma； Cell Death & Disease
168. （2019）Periodic-Mechanical-Stimulus Enhanced Osteogenic Differentiation of Mesenchymal Stem Cells on Fe3O4/Mineralized Collagen Coatings； ACS Biomaterials Science & Engineering
169. （2019）Synergistic effect of a retinoid X receptor-selective ligand bexarotene and docetaxel in prostate cancer； Onco Targets and therapy
170. （2019）Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells； Journal of Cancer
171. （2018）Redox State of PDA Directs Cellular Responses through Preadsorbed Protein； ACS Biomaterials Science & Engineering
172. （2018）Leukemia inhibitory factor promotes extracellular matrix synthesis in degenerative nucleus pulposus cells via MAPK-ERK1/2 signaling pathway； Biochemical and Biophysical Research Communications
173. （2018）Linc00961 inhibits the proliferation and invasion of skin melanoma by targeting the miR?367/PTEN axis； InternationalJournal ofOncology
174. （2018）N-(3-oxododecanoyl)-l-homoserine lactone modulates mitochondrial function and suppresses proliferation in intestinal goblet cells； Life sciences
175. （2018）Developmental Exposure to Di-(2-ethylhexyl) Phthalate Induces Cerebellar Granule Cell Apoptosis via the PI3K/AKT Signaling Pathway； Experimental neurobiology
176. （2018）Bisphenol A suppresses proliferation and induces apoptosis in colonic epithelial cells through mitochondrial and MAPK/AKT pathways； Life Sciences
177. （2018）DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling； Cell Research
178. （2018）Genome-wide screening for functional long noncoding RNAs in human cellsby Cas9 targeting of splice sites； Nature Biotechnology
179. （2017）Investigation of G-quadruplex formation in the FGFR2 promoter region and its transcriptional regulation by liensinine； Biochimica et Biophysica Acta (BBA) - General Subjects
180. （2016）Hydrogen peroxide mediated mitochondrial UNG1-PRDX3 interaction and UNG1 degradation； Free Radical Biology and Medicine
181. （2016）Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library； Nature biotechnology